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Sunday, May 15, 2011

IRAN SCIENCE- Nano, Stem Cells Technologies Employed in Fabrication of Bone Scaffolds http://www.islamidavet.com/english/2011/05/14/nano-stem-cells-technologies-employed-in-fabrication-of-bone-scaffolds/

Researchers at Royan Institute, Iran Polymer and Petrochemical Institute and Amirkabir University of Technology collaboratively took a step in the advancement of tissue engineering by combining two state-of-the-art technologies i.e. stem cells and nanotechnology.“The main objective of our research work was to fabricate an optimum osteogenic structure via tissue engineering techniques,” Mohammad R. B. Eslaminejad, researcher with Royan Institute, said, and added,

“To fulfill such an aim, mesenchymal and scaffold stem cells of nano/micro dimensions were utilized and their effectiveness was investigated.”Eslaminejad went on to say, “In tissue engineering practices, the employed scaffold has to be similar to the extra cellular matrix of the target tissue. In this regard, we synthesized polylactic acid/nano hydroxyl apatite scaffolds.” 

“The composite of the mentioned materials offers most favorable mechanical properties and provides enhanced osteogenic connections. Thanks to the nano metric dimensions of the applied hydroxyl apatite particles, the obtained scaffold bears a close resemblance to its natural counterpart.” “Another positive point on this research is the application of mesenchymal stem cells. Such cells are non-immunogenistic and of interest for their special multiplicative characteristics,” he added. 

As the initial stage of the work, the fabricated scaffolds were examined for their structural and mechanical properties. Subsequently, mesenchymal stem cells derived from bone marrow were purified and assessed. Afterwards, the cells were placed in the scaffolds and their biocompatibilities as well as some other characteristics were studied. The results ascertain the superiority of osteogenic composites comprised of mesenchymal stem cells and nanostructured scaffolds.

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Iran had some significant successes in nuclear technology during recent decades, especially in nuclear medicine. However, little connection exists between Iran's scientific society and that of the nuclear program of Iran. Iran is the 7th country in production of uranium hexafluoride (or "UF6").[70] Iran now controls the entire cycle for producing nuclear fuel.

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[71] Iranian scientists are also helping to construct the Compact Muon Solenoid, a detector for the Large Hadron Collider of the European Organization for Nuclear Research (CERN) that is due to come online in 2008[citation needed]. Iranian engineers are involved in the design and construction of the first regional particle accelerator of the Middle East in Jordan, called SESAME.

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[72] In 2009, Iran was developing its first domestic Linear particle accelerator (LINAC).[73] It is among the few countries in the world that has the technology to produce zirconium alloys.[74][75] Iran produces a wide range of lasers in demand within the country in medical and industrial fields.[69] In 2011, Iranian scientists at the Atomic Energy Organization of Iran (AEOI) have designed and built a nuclear fusion device, named IR-IECF.[76] Iran is the 6th country with such technology.[76

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Iran was ranked 15th in NANOTECHNOLOGY by 2009 in the world ranking.[91][92] In 2007 Iranian scientists at the Medical Sciences and Technology Center succeeded in mass producing an advanced scanning microscope—the Scanning Tunneling Microscope (STM).[93]

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